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James D Crapo Selected Research

AEOL 10150

4/2003Evidence for extracellular superoxide dismutase as a mediator of hemorrhage-induced lung injury.
10/2002Inhibition of tobacco smoke-induced lung inflammation by a catalytic antioxidant.
10/2002A catalytic antioxidant (AEOL 10150) attenuates expression of inflammatory genes in stroke.
10/2002Effects of metalloporphyrin catalytic antioxidants in experimental brain ischemia.

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James D Crapo Research Topics

Disease

83Chronic Obstructive Pulmonary Disease (COPD)
07/2022 - 12/2002
26Emphysema
04/2021 - 07/2011
16Inflammation (Inflammations)
11/2018 - 08/2002
8Neoplasms (Cancer)
01/2017 - 03/2004
7Chronic Bronchitis
07/2019 - 04/2014
6Lung Injury
03/2012 - 04/2002
5Dyspnea (Shortness of Breath)
07/2021 - 08/2011
5Lung Diseases (Lung Disease)
04/2018 - 06/2003
5Pneumonia (Pneumonitis)
09/2015 - 10/2002
5Ischemia
06/2006 - 10/2002
4Infections
11/2021 - 08/2009
4Asthma (Bronchial Asthma)
07/2019 - 08/2002
4Hypoxia (Hypoxemia)
12/2018 - 08/2006
4Bronchopulmonary Dysplasia
10/2011 - 01/2003
3Disease Progression
11/2021 - 08/2016
3Obstructive Lung Diseases (Obstructive Lung Disease)
10/2020 - 09/2015
3Fibrosis (Cirrhosis)
01/2017 - 03/2003
3Prostatic Neoplasms (Prostate Cancer)
01/2012 - 01/2009
3Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
10/2009 - 10/2002
3Cardiomyopathies (Cardiomyopathy)
06/2006 - 03/2003
2Hypertension (High Blood Pressure)
07/2019 - 01/2016
2Idiopathic Pulmonary Fibrosis
01/2019 - 01/2016
2Glioma (Gliomas)
01/2016 - 02/2010
2Lymphoma (Lymphomas)
04/2012 - 07/2009
2Pulmonary Fibrosis (Fibrosing Alveolitis)
03/2012 - 04/2002
2Hemorrhage
01/2012 - 04/2003
2Neurologic Manifestations (Neurological Manifestations)
10/2009 - 10/2002
2Premature Birth (Birth, Premature)
03/2009 - 03/2005
2Myocardial Ischemia (Ischemic Heart Diseases)
05/2003 - 03/2003
2Infarction (Infarctions)
05/2003 - 10/2002
2Hyperoxia
01/2003 - 11/2002
1Chronic Disease (Chronic Diseases)
10/2020
1Pruritus (Itching)
07/2019
1Atopic Dermatitis (Atopic Eczema)
07/2019
1Psoriasis (Pustulosis Palmaris et Plantaris)
07/2019
1Metabolic Syndrome (Dysmetabolic Syndrome X)
04/2018
1Osteoporosis
04/2018
1Cardiovascular Diseases (Cardiovascular Disease)
04/2018
1Type 1 Diabetes Mellitus (Autoimmune Diabetes)
01/2018

Drug/Important Bio-Agent (IBA)

32GoldIBA
07/2022 - 02/2010
25AntioxidantsIBA
12/2016 - 05/2002
23Biomarkers (Surrogate Marker)IBA
01/2020 - 04/2003
15Superoxide DismutaseIBA
01/2013 - 03/2002
14PorphyrinsIBA
11/2021 - 10/2002
11ManganeseIBA
11/2021 - 04/2003
11SmokeIBA
08/2017 - 09/2002
8Oxygen (Dioxygen)IBA
07/2021 - 12/2002
8Reactive Oxygen Species (Oxygen Radicals)IBA
04/2012 - 10/2002
8Superoxides (Superoxide)IBA
02/2010 - 12/2002
7MetalloporphyrinsIBA
11/2021 - 10/2002
7Proteins (Proteins, Gene)FDA Link
01/2019 - 08/2006
7Bronchodilator Agents (Bronchodilators)IBA
07/2017 - 07/2011
6Pharmaceutical PreparationsIBA
07/2019 - 12/2006
5CytokinesIBA
10/2017 - 09/2007
5EnzymesIBA
09/2008 - 05/2002
4manganese tetrakis-(N-ethyl-2 pyridyl) porphyrinIBA
11/2021 - 01/2009
4Biological ProductsIBA
01/2019 - 01/2017
4Free RadicalsIBA
08/2009 - 04/2002
4AEOL 10150IBA
04/2003 - 10/2002
3Pulmonary Surfactant-Associated Protein D (Surfactant Protein D)IBA
11/2019 - 12/2012
3C-Reactive ProteinIBA
11/2019 - 12/2012
3GlucocorticoidsIBA
05/2015 - 07/2009
3Nitric Oxide (Nitrogen Monoxide)FDA Link
03/2009 - 03/2003
3Oxidants (Oxidizing Agents)IBA
01/2009 - 08/2002
2Anti-Bacterial Agents (Antibiotics)IBA
11/2021 - 10/2014
2UteroglobinIBA
11/2019 - 12/2012
2Fibrinogen (Factor I)FDA Link
11/2019 - 12/2012
2ChemokinesIBA
10/2017 - 03/2003
2Interleukin-6 (Interleukin 6)IBA
10/2017 - 04/2010
2Adrenal Cortex Hormones (Corticosteroids)IBA
01/2016 - 10/2014
2CholesterolIBA
01/2016 - 03/2012
2DNA (Deoxyribonucleic Acid)IBA
08/2015 - 02/2010
2SteroidsIBA
05/2015 - 12/2006
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
12/2012 - 04/2010
2indium-bleomycinIBA
03/2012 - 04/2002
2Bleomycin (Blenoxane)FDA LinkGeneric
03/2012 - 04/2002
2nasIBA
02/2012 - 12/2011
2Pancreatic Elastase (Elastase)IBA
10/2011 - 08/2010
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
04/2010 - 08/2006
2BombesinIBA
11/2007 - 01/2003
2Peptides (Polypeptides)IBA
11/2007 - 01/2003
2manganese (III) meso- tetrakis(N- ethylpyridinium- 2- yl)porphyrinIBA
02/2006 - 05/2003
11-methylpyridiniumIBA
11/2021
1Gonadal Steroid Hormones (Sex Hormones)IBA
04/2020
1Carnitine O-Palmitoyltransferase (Carnitine Palmitoyltransferase II)IBA
12/2019
12- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA
12/2019
1Surface-Active Agents (Surfactants)IBA
11/2019
1Receptor for Advanced Glycation End ProductsIBA
11/2019
1ethylpyridiniumIBA
07/2019
1RetinoidsIBA
01/2019
1Metalloproteases (Metalloproteinases)IBA
11/2018
1Factor V (Coagulation Factor V)IBA
10/2018
1H-cadherin (T-cadherin)IBA
04/2018
1AdiponectinIBA
04/2018

Therapy/Procedure

15Therapeutics
11/2021 - 03/2003
6Radiotherapy
01/2017 - 09/2007
2Pneumonectomy (Lung Volume Reduction)
01/2018 - 01/2017
1Orthopedic Procedures
11/2021
1Activities of Daily Living (ADL)
07/2021
1Islets of Langerhans Transplantation
01/2018